Caspase-3 Activation Assay Cell Line

Description A novel Caspase 3-7 Activity Assay Cell Line has been developed in SH-SY5Y cell line through stable transfection with a caspase 3-7 activation reporter protein endogenously linked with FP602. When caspase 3-7 is activated, link is cleavaged and FP602 change its localization appearing in the nucleus. This cell line allows to monitor apoptosis by caspase 3-7 activation, quantifying the red fluorecence intensity inside the cell nucleus. It is guaranteed that these cells will expand following the cell culture manual.